Medical news update

- Self-Administered Etripamil and Emergency Department Visits in Supraventricular Tachycardia
This secondary analysis of a randomized clinical trial describes the use of emergency care after self-administration of etripamil by patients experiencing paroxysmal supraventricular tachycardia […]
- Rural America—Expanding the Lens of Health Disparities
He who has health, has hope; and he who has hope has everything.Thomas Carlyle
- Genetic Testing in Early-Onset Atrial Fibrillation
Atrial fibrillation (AF) occurs commonly in patients with cardiomyopathy (CMP). For example, the prevalence of AF in patients with hypertrophic CMP is 20% to 30%, which is 4- to 6-fold higher than […]
- The Role of Cardiovascular Disease Journals in Reporting Sex and Gender in Research
Understanding sex and gender is critical to promoting human health and targeting disease. Although sex is often incorrectly thought to have the same meaning as gender, the terms describe different […]
- Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Diabetes
This prespecified subgroup analysis of the FAME 3 randomized clinical trial investigates the relative treatment effect of fractional flow reserve (FFR)–guided percutaneous coronary intervention vs […]
- Valsartan and Cardiac Remodeling in Early-Stage Hypertrophic Cardiomyopathy
This prespecified substudy of the VANISH randomized clinical trial evaluates the treatment effects of valsartan on myocardial structure, function, and tissue parameters in early-stage sarcomeric […]
- Temporary Mechanical Cardiac Support Outcomes and Cardiogenic Shock
To the Editor We read with interest the recent substudy of the DanGer Shock randomized trial, which showed that the use of a microaxial flow pump (mAFP) leads to hemodynamic stability reducing the […]
- Aortic Valve Intervention for Asymptomatic Aortic Stenosis
This Viewpoint discusses the use of aortic valve intervention vs watchful waiting for patients with asymptomatic aortic stenosis.

- Detection bias and the role of negative control outcomes
- Detection bias and the role of negative control outcomes
- Risk factors, impact, and healthcare use related to initial suicide attempts: comprehensive analysis of Swedish population
- Risk factors, impact, and healthcare use related to initial suicide attempts: comprehensive analysis of Swedish population
- Association between maternal body mass index and hospital admissions for infection in offspring: longitudinal cohort study
- Association between maternal body mass index and hospital admissions for infection in offspring: longitudinal cohort study
- Metformin for covid-19: systematic review and meta-analysis of randomised controlled trials
- Metformin for covid-19: systematic review and meta-analysis of randomised controlled trials
- Ending nuclear weapons, before they end us
- Ending nuclear weapons, before they end us

- Limitations of constant sodium estimates: a response to Song et al.
No abstract available
- Response to Wuopio et al.: Concerns regarding the use of inappropriate statistical methods and unreliable references
No abstract available
- Editorial commentary on: “assessing the relationship between short-term blood pressure variability and glycation profile in young and middle-aged nondiabetic hypertensive individuals”
No abstract available
- The European Society of Cardiology got it wrong: their target systolic blood pressure in chronic kidney disease patients is not low enough!
No abstract available
- Hypertension determinants among Ghanaians differ according to location of residence: RODAM study: Erratum
No abstract available
- Spironolactone protects against hypertension-induced renal fibrosis by promoting autophagy and inhibiting the NLRP3 inflammasome
Introduction: We aimed to investigate the mechanism by which spironolactone protects against hypertensive renal fibrosis. Methods: For in-vivo experiments, we established Control, SHR, and […]
- Hypertension accelerates the development of a diabetic nephropathy model with more relevant clinical features in Dahl salt-sensitive rat
Objective: Diabetic nephropathy is becoming an increasing health problem and the major cause of chronic kidney disease. The lack of experimental models that reproduce all structural and […]
- DDX17 deficiency inhibits the proliferation and migration of vascular smooth muscle cells by inhibiting RHEB/mTORC1-mediated glycolysis and oxidative stress
As an RNA-binding protein, DEAD-box RNA helicase 17 (DDX17) plays a critical role in influencing gene expression and participates in the proliferation and migration of several cell lines. The current […]

- ESH 2026
INNOVATIONS IN CARDIOMETABOLIC MANAGEMENT
- ESH MASTERplan for Hypertension Management in CKD – webinars
Did you miss the webinar “ESH MASTERplan for Hypertension Management in CKD”? The recording is now available HERE
- Summer School 2025
Date: 14-19 September 2025 Venue: Särö (Gothenburg), Sweden
- NEW ESH 2024 webinars
Webinar 1: Key Points of the Hypertension Guidelines - The ESH MASTERplan for hypertension Webinar 2: Managing Hypertensive Patients in Clinical Practice – Update on the management of […]
- ESH Webinars 2024
PART 1: Updates on resistant hypertension from novel lifestyle interventions to new drugs and interventional therapies PART 2: Hypertension treatment challenges and options in comorbidities
- ESH 2024
BERLIN MAY 31 - JUNE 3, 2024 www.eshannualmeetings.eu Abstracts are available in Journal of Hypertension
- NEW EUROPEAN GUIDELINES
The final version of the full guidelines is now available on the Journal of Hypertension website.
- Webinar series
HOT TOPICS IN HYPERTENSION MANAGEMENT - AUTUMN 2020 (Part 2) - NOW AVAILABLE.

- Cardioprotective and Anti‐Hypertensive Effects of Epigallocatechin Gallate: Novel Insights Into Biological Evidence
The Journal of Clinical Hypertension, Volume 27, Issue 6, June 2025.
- Efficacy and Safety of Catheter‐Based Renal Denervation for Patients With Hypertension: A Systematic Review and Meta‐Analysis
The Journal of Clinical Hypertension, Volume 27, Issue 6, June 2025.
- Clinical relevance of double‐arm blood pressure measurement and prevalence of clinically important inter‐arm blood pressure differences in Indian Primary Care
The Journal of Clinical Hypertension, Accepted Article.

- Profiles of echocardiographic features associated with blood pressure in patients with hypertension
Journal of Human Hypertension, Published online: 05 June 2025; doi:10.1038/s41371-025-01034-4Profiles of echocardiographic features associated with blood pressure in patients with hypertension
- Safety and efficacy of alcohol-mediated bilateral adrenal artery embolization in patients with idiopathic hyperaldosteronism: a 6-month follow-up of a randomized controlled trial
Journal of Human Hypertension, Published online: 04 June 2025; doi:10.1038/s41371-025-01032-6Safety and efficacy of alcohol-mediated bilateral adrenal artery embolization in patients with idiopathic […]
- Comparison of ambulatory blood pressure monitoring among patients with postural orthostatic tachycardia syndrome, autonomic dysfunction, and controls
Journal of Human Hypertension, Published online: 30 May 2025; doi:10.1038/s41371-025-01031-7Comparison of ambulatory blood pressure monitoring among patients with postural orthostatic tachycardia […]
- Long-term effect of continuous positive airway pressure on blood pressure in patients with resistant hypertension and obstructive sleep apnea
Journal of Human Hypertension, Published online: 28 May 2025; doi:10.1038/s41371-025-01030-8Long-term effect of continuous positive airway pressure on blood pressure in patients with resistant […]
- Baroreceptor sensitivity, kidney function and cardiovascular risk in prepubescent boys with normal versus elevated blood pressure
Journal of Human Hypertension, Published online: 28 May 2025; doi:10.1038/s41371-025-01029-1Baroreceptor sensitivity, kidney function and cardiovascular risk in prepubescent boys with normal versus […]
- A new approach to interpreting the LF/HF ratio: a study in hypertensive patients
Journal of Human Hypertension, Published online: 23 May 2025; doi:10.1038/s41371-025-01028-2A new approach to interpreting the LF/HF ratio: a study in hypertensive patients
- Multiple system biology approaches reveals the role of the hsa-miR-21 in increasing risk of neurological disorders in patients suffering from hypertension
Journal of Human Hypertension, Published online: 20 May 2025; doi:10.1038/s41371-025-01027-3Multiple system biology approaches reveals the role of the hsa-miR-21 in increasing risk of neurological […]
- Association of ambient temperature and blood pressure in the Jackson Heart Study
Journal of Human Hypertension, Published online: 15 May 2025; doi:10.1038/s41371-025-01026-4Association of ambient temperature and blood pressure in the Jackson Heart Study
- Does Elevated Neutrophil-to-Lymphocyte Ratio Predict Worse Outcomes in Acute Myocarditis?
Yes, based on data from a large patient cohort.
- A Randomized Trial of Fluid Restriction Advice for Heart Failure
In an ambulatory cohort with mild-to-moderate symptoms, advising daily fluid restriction provided no benefit.
- Amiloride for Patients with Resistant Hypertension?
In patients with resistant hypertension, amiloride and spironolactone have similar — and impressive — effects on home blood pressure.
- More Data on Lp(a): This Time on Recurrent ASCVD Risk
A higher Lp(a) level was associated with greater risk for a recurrent ASCVD event.
- New Life for a Failed Drug Class
An oral CETP inhibitor — both alone and combined with ezetimibe — significantly reduced LDL-C in high-risk patients already on cholesterol-lowering therapies.
- Support for Moderate-Intensity Statin plus Ezetimibe in Older Patients
Compared with high-intensity statins, this alternate regimen lowered LDL-C similarly, with significantly fewer muscle symptoms, in patients 70 and older.
- Can Electronic Provider Notification Improve Outcomes in Severe Aortic Stenosis?
A randomized trial provides a strong signal of benefit.
- Do Patients with Histories of Takotsubo Syndrome Have Increased Long-Term Morbidity?
Yes, and not all of the morbidity is cardiovascular.